Jardiance® (Empagliflozin) Tablets

What Is Jardiance®?

Jardiance® contains empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It works by helping the kidneys remove excess glucose from the bloodstream through urine, thereby lowering blood sugar levels.

Clinical guidance from the National Institute for Health and Care Excellence (NICE) supports the use of SGLT2 inhibitors in appropriate individuals with type 2 diabetes, particularly where cardiovascular or renal benefit is desired. In the UK, regulatory oversight is provided by the Medicines and Healthcare products Regulatory Agency (MHRA).

Available Strengths

• 10 mg film-coated tablets
• 25 mg film-coated tablets

How Jardiance® Works

Empagliflozin blocks the SGLT2 protein in the kidneys, reducing glucose reabsorption and increasing urinary glucose excretion. This leads to lower circulating blood sugar levels. The mechanism is insulin-independent, meaning it works regardless of pancreatic beta-cell function.

In addition to glycaemic control, empagliflozin has demonstrated cardiovascular and renal benefits in suitable patients.

Dosage and Administration

Route: Oral administration.

• Initial dose for type 2 diabetes: 10 mg once daily.
• Dose escalation: May be increased to 25 mg once daily if additional glycaemic control is required.
• Heart failure: Recommended dose is 10 mg once daily.

Tablets should be swallowed whole with water and may be taken with or without food. It is advisable to take the medication at the same time each day, typically in the morning.

Important Considerations

• Missed dose: Take as soon as remembered unless it is nearly time for the next dose. Do not take a double dose.
• Renal monitoring: Kidney function should be assessed before initiation and monitored periodically during treatment.
• Hydration: Adequate fluid intake is recommended to reduce the risk of dehydration.

Benefits of Jardiance®

• Cardiovascular protection: Reduces the risk of cardiovascular death in adults with type 2 diabetes and established heart disease.
• Blood pressure reduction: Modest reductions in blood pressure have been observed.
• Weight reduction: Some patients experience weight loss due to glucose excretion.
• Renal protection: May slow progression of kidney disease in appropriate individuals.
• Low hypoglycaemia risk: When used alone or with non-hypoglycaemic agents.
• Once-daily dosing: Convenient administration supports adherence.

Possible Side Effects

Common

• Increased urination
• Urinary tract infections
• Genital fungal infections

Serious

• Dehydration and low blood pressure
• Diabetic ketoacidosis (DKA)

Seek urgent medical attention if symptoms such as nausea, vomiting, abdominal pain, excessive thirst, or confusion occur.

Who Should Not Take Jardiance®?

• Individuals with severe renal impairment, end-stage renal disease, or those on dialysis.
• Patients with a history of diabetic ketoacidosis.
• Women who are pregnant or breastfeeding.

Buying Jardiance® Online

Jardiance® is a prescription-only medicine. Patients considering online purchase should ensure the pharmacy is legitimate and regulated.
Review our shipping information for delivery timelines.

1. Select the prescribed dosage (10 mg or 25 mg).
2. Provide a valid prescription.
3. Complete checkout securely.

Always consult your healthcare professional before starting or modifying treatment.